The most frequently used drugs are tricyclic antidepressants, which received their name from the organization of their chemical structures, in particular the systems consisting of two benzene rings joined to a central 7-membered ring with a dialkylaminoalkyl…

For the past two years our increasing knowledge of migraine’s biogenesis has been paralleled by an explosion of new therapies unprecedented in their biologic selectivity and clinical effectiveness. While these medications provide us with a potent arsenal…