Oral Diabetic Medications : List of Common Diabetes Medications

Oral diabetic medications Intended primarily to help the management of patients with Type II diabetes mellitus. how to choose a diabetes medication that is right determine the success of diabetes therapy.

Depending on the severity of the disease and the condition of the patient, pharmacotherapy oral hypoglycemic can be done by using one type of drug or a combination of the two types of drugs.

The selection and determination of a regimen of hypoglycemic agents used should consider the severity of the diabetes (the level of glycemia) as well as the condition of the patient's general health including other diseases and complications. see also: Alert Diabetes in adolescents.
( Read more : type 2 diabetes medications list )

Oral Diabetic Medications


1. Class Sulfonylureas

Mechanism of action : Stimulation of insulin secretion from the beta cells in the pancreas

Drugs :

  • Chlorpropamide

  • Dosage : Start 125-250mg per day, Maximum : 250-500mg per day ; Rules of use : Taken with meals

  • Glibenclamide

  • Dosage : 2.5-5mg per day. Start at 1.25 mg for patients who are prone to hypoglycemic, Maximum : 15-20mg per day ; Rules of use : Taken with meals

  • Glikazid

  • Dosage : Initial 40-80 mg per day ; Maximum : 320mg per day, to doses of > 160mg can be given in divided doses, for the preparation of Modified Release (MR) formulation can be administered in a dose of 30-120mg once daily ; Rules of use : Taken with meals.

  • Glimepirid

  • an initial DoseDosage of 1mg per day titrate dose according to patient's response multiples 1mg in intervals of 1-2 weeks ; Maximum : 6-8mg per day ; dosage : Taken before first meal (breakfast)

  • Glipizid

  • an initial Dosage of 1mg per day ; Maximum 20mg per day, For a dose > 15mg given in divided doses

  • Glikuidon

  • an initial DoseDosage of 15mg per day, can be increased to 45-60mg per day in 2-3 divided doses ; Maximum dose : 120mg per day ; Rules of use : Taken with meals

  • Tolazamid

  • an initial Dosage of 100mg 1-2 times daily, maintenance Dose : 100-300mg per day in divided doses ; Maximum Dose : 500mg per day

  • Tolbutamide

  • 1-2g per day in divided doses, maintenance Dose : 0.25-2g per day, a Maximum of : 3g per day

    2. Class Biguanid

    Mechanism of action : Reduce the process of gluconeogenesis in the liver stimulant glycolysis and improve the work of insulin in muscle tissue and fat

    Drugs :

  • Buformin

  • Dosage : 50mg 3 times daily, Maximum dose : 300mg per day

  • Metformin

  • an initial Dose of 500mg per day for 1 week, followed by a dose of 500mg 2 times a day in the next week, up to a dose of 500mg per day ; Or with the initial dose 850mg 2-3 times daily, maximum Dose : 2-3g per day ; Rules of use : Drink with food
    3. Class Alpha-Glucosidase Inhibitors

    Mechanism of action : Lowers the absorption of carbohydrates, dextrin, and disaccharides in the intestine, so can reduce the rise in plasma glucose at the time after a meal.

    Drugs :

  • Acarbose

  • initial Dose : 50mg per day, can be increased to 50mg 3 times a day, and if necessary, the dose can be increased to 100mg 3 times daily, Maximum dose : 200mg 3 times a day

  • Voglibose

  • initial Dose of 0.2 mg 3 times daily, can be increased to 0.3 mg per day

    4. Class Meglitinid

    Mechanism of action : Stimulates the production of insulin more powerful in the pancreas but cannot be continuous

    Drugs :

  • Nateglinid

  • initial Dose : 120mg 3 times daily, maximum Dose : 180mg 3 times a day ; dosage : Taken 1-30 minutes before meals

  • Repaglinid

  • initial Dose : 500mcg, can be improved depending on the repons of the patient in intervals of 1-2 weeks, Maximum dose : 16mg per day. For the use of doses > 4mg, can be given in divided doses, Rules of use : Drink before meals, or 15 minutes before a meal

    5. Class Thiazolidindion

    Drugs :

  • Pioglitazon

  • Can be initiated with doses of 15 or 30mg once daily, Maximum dose : 45mg per day, the Rules of use : With or without food

  • Rosiglitazon

  • Dosage : 4 mg daily, and can be increased up to 8 mg per day in 1-2 divided doses after 8-12 weeks of usage (combined with insulin) or 12 weeks (combined with metformin), Rules of use : With or without food.

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