Targeted Therapy : New Hope Ovarian Cancer Survival Rate

Ovarian cancer survival rate, Ovarian cancer is a cancer that grows on the ovaries or the ovaries. The disease occupied the seventh position among the types of cancer that most commonly affects women. Every year, there are about 250,000 cases of ovarian cancer in the whole world, which led to 140,000 deaths per year.

This cancer can appear in all age groups, but generally occurs in women who have entered menopause or are over the age of 50 years. ( Read more : colon cancer test and multiple sclerosis medications )

ovarian cancer survival rate

New ovarian cancer survival rate 

Patients of ovarian cancer now have new hope with the approval of innovative therapies based on targeted therapy . It became a new stage in the management of ovarian cancer who previously relied on surgery and chemotherapy. 

Targeted therapy this is the first time approved in 2011 by the European Commission based on the results of two major research done in Europe and America, and is approved as first-line treatment of cancer in advanced ovarian cancer patients.

"Targeted therapy is positive in improving the quality of life of the sufferer and gives much longer life expectancy of up to 27% in advanced stage patients," said Sven Mahner, doctor of oncology of the University Medical Center Hamburg-Eppendorf, Department of Gynecology and Gynecological Oncology.

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Type of Ovarian Cancer

Ovarian cancer is classified into 3 types, based on the location of the beginning of the development of cancer :
  • Epithelial tumors, cancer cells appear on the network wrapping the ovaries. This is a type of ovarian cancer that occur most commonly.

  • Stromal tumours, cancer appears on the layer where is located the cells producing the hormone. This type of cancer including rare. Only about 7 in between 100 cases of ovarian cancer which is a type of this.

  • Germ cell tumors, cancer develops in cells that produce eggs. The type of ovarian cancer is more likely to occur in women of young age.
Symptoms Of Ovarian Cancer

Cancer of the ovaries rarely cause symptoms in its early stages. If anything, the symptoms resemble constipation or symptoms in irritable bowel. Therefore, ovarian cancer is usually detected when the cancer has already spread in the body.

Some of the symptoms commonly experienced by patients with ovarian cancer are :
  • Stomach always feels bloated.
  • Swelling of the abdomen.
  • Abdominal pain.
  • Weight loss.
  • Quick of satiety.
  • Nausea.
  • Change in bowel habit, eg constipation (difficult bowel movements).
  • Frequency of urination increased.
  • Pain during sexual intercourse.
Causes and Risk Factors of Ovarian Cancer

The same as cancer in general, the causes of ovarian cancer are not known with certainty. There are several factors that allegedly can increase a woman's risk for developing cancer. Such factors include :
  • Age. Ovarian cancer tends to occur in women aged 50 years and over.

  •  Genetic. The risk for developing ovarian cancer will be increased if you have family members who have ovarian cancer or breast cancer. So also in women who have BRCA1 and BRCA2, which is a genetic mutation that can be passed down.

  • Estrogen hormone replacement therapy (Estrogen Hormone Replacement Therapy), especially when done in the long term and with high doses.

  • Suffering from polycystic ovarian syndrome (PCOS).

  • Never having been pregnant.

  • Having excess weight or obesity.

  •  Experienced a menstrual cycle before age 12 and menopause after the age of 50 years.

  • Undergoing fertility treatments.

  • Smoking.

  • Using IUD contraception.
ovarian cancer survival rate

Treatment Of Ovarian Cancer

Handling ovarian cancer can be different in each case, determined based on the stage of the cancer, health conditions, and the desire of patients to have offspring. The handling of primary ovarian cancer is through surgery and chemotherapy or radiotherapy.

1. Operation

Surgery procedure usually includes the removal of both ovaries, fallopian tubes, uterus, and omentum (fatty tissue in the abdomen). This surgery can also involve removal of the lymph nodes in the pelvis and abdominal cavity to prevent and find out if there is spread of the cancer. With the removal of both ovaries and the uterus, the patient can no longer have offspring.

Yet another case of ovarian cancer detected in early stage. The sufferer may just be undergo surgical removal of one ovary and fallopian tube so it is likely to have descendants still there.

2. Chemotherapy

Chemotherapy can be scheduled after surgery. This is done to kill cancer cells remaining. During chemotherapy, the doctor will monitor the progress of patients regularly to ensure the effectiveness of the drug and the body's response to drugs.

Chemotherapy can also be given before surgery in patients with advanced ovarian cancer, with the aim to shrink the tumor so as to facilitate the appointment procedure.

Every treatment carries the risk of side effects, so it is with chemotherapy. Some of the side effects that may occur after the process of chemotherapy which is not of appetite, nausea, vomiting, weakness, hair loss, and increased risk of infection.

3. Radiotherapy

In addition to surgery and chemotherapy, radiotherapy is another action that can be an alternative. In radiotherapy, cancer cells killed using radiation from x rays.

Like chemotherapy, radiotherapy can be given either after or before surgery. Side effects are also similar with chemotherapy, especially the occurrence of hair loss.

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Stage Of Ovarian Cancer

If the results of the examination show someone positive suffering from ovarian cancer, the next step to do is to determine the level of spread of the cancer. In determining the rate of spread of ovarian cancer, examination can be done with a CT or MRI scan, chest x-rays, and examination of a sample of fluid the abdominal cavity and the ovarian tissue.

Determine the rate of spread of cancer will help the doctor to determine the best treatment.

In general, the rate of spread of ovarian cancer is divided into four stages, namely :
  • Stage 1: the Cancer is only attacking one or both ovaries, but has not spread to other organs.
  • Stage 2: Cancer has spread from the ovary to tissues within the pelvis or uterus.
  • Stage 3: Cancer has spread to the lining of the stomach, the surface of the intestines, and lymph nodes in the pelvis or abdomen.
  • Stage 4: Cancer has spread to other parts of the body, for example kidneys, liver, and lungs.
Prevention Of Ovarian Cancer

Because the cause is unknown, prevention of ovarian cancer also could not be done for sure. However there are some things that can lower the risk of someone affected by cancer. Such measures include :
  • Use of contraception in pill form over the past 10 years. This step is proven to reduce the risk of ovarian cancer by half.
  • Undergo pregnancy and lactation.
  • Implement a healthy lifestyle to avoid obesity for Example is to exercise regularly and increase the consumption of fiber such as fruits and vegetables.
In women who have a high risk of developing cancer of the ovaries, surgical removal of the ovaries and fallopian tubes before cancer can also be done in order to minimize the risk. This procedure is usually recommended at the age of 35 to 40 years, for those who've decided not to have offspring again.

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