What causes lupus ? Here symptoms, causes and define lupus you should know !


What is lupus disease and How do you get lupus ? Lupus disease is a disorder of the immune system that occur in the body. This disease belongs to the autoimmune disease that causes the cells of the body are damaged and inflamed.

Lupus is a condition in which the body produces antibodies in excess. In normal circumstances, antibodies serve to protect the body from various foreign substances that can cause disease.

However, in people who experience lupus disease (Odapus), the antibodies that it has actually attack the cells of his own body. So, odapus easily subjected to disease infection and inflammation – a result of healthy cells being attacked by antibodies.

The causes of the occurrence of lupus in a person to date is not yet known. So far, the suspected lupus symptoms in women compared with men is influenced by several genetic and environmental factors.

Lupus including disease rarely occurs. Although not yet known the exact figures, but in Indonesia itself, people who experience this disease there are about 12.700 inhabitants in the year 2012. Incidence of the disease is then increased to 13.300 in 2013.

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What causes lupus and symptoms ? Here define lupus you should know

Most of the people who have the disease lupus are female. It was reported that as many as 90% of cases of lupus that occur experienced by women. The reason it is not yet known with certainty until now. But, a study published in the Annals of the Rheumatic Disease said that if it is associated with chromosomal genes owned by women.

In addition, most cases of lupus detected in patients aged 15-45 years. However, do not close the possibility of this condition occurring in children and parents.

Types of lupus disease

There are several types of lupus disease, namely :
  • Systemic lupus erthematosus (SLE), is a type of lupus that occurs most frequently. This type of disease is attacking various tissues such as, joints, skin, brain, lungs, kidneys, and blood vessels.
  • Discoid lupus erthematosus, is a type of lupus that attacks the tissues of the skin, causing rashes.
  • Neonatal lupus is the disease lupus that strikes newborns. The disease experienced by babies born to mothers who have abnormalities of the antibody.
  •  Lupus caused by drugs, this disorder is usually only experienced in a short time. So some drugs may cause side effects, which symptoms are similar to lupus. The patient's condition will improve if drug use is stopped.
  • Subacute cutaneous lupus erythematosus, is lupus that makes the skin tissue wound and burn when exposed to sunlight.



Lupus symptoms and signs

Lupus is a disease that is known as ‘the disease of 1000 faces’. This designation arises due to chronic disease is cause symptoms and signs similar to other diseases. So, the disease is likely to be difficult to be detected early. Here are some signs and symptoms that are usually experienced by the odapus, according to the American College of Rheumatology:
  • Joint pain
  • Swollen joints
  • The mouth or the nose had a wound that didn't heal in days to months.
  • In the urine there is blood or even protein (proteinuria)
  •  There are rash-rash in various skin surface
  • Hair loss
  • Fever
  • Seizures-seizures
  • Chest pain and difficult breathing due to inflammation in the lungs
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What causes lupus and symptoms ? Here define lupus you should know

Lupus causes

Lupus is a chronic disease caused by disorder in the body, so it is definitely not a virus or bacteria is the primary cause. In fact, experts do not yet know exactly what causes lupus. There are many factors that may cause this. However, some theories stating that the disease of lupus caused due to the presence of the interaction of genes, hormones, and the environment.

1. Genetic factors

Researchers from the John Hopkins Center, first attracted by the cause of the disease lupus, of the relationship between gene family with the sufferers. In fact, the existence of patients with lupus in a family, can increase the tendency of lupus disease on other family members. In addition, the family members of lupus patients, when performing medical tests, tend to be a positive result.

Then, with the presence of genes that trigger the development of a disease, does not mean the person can be directly exposed to or can pass the disease lupus. In another case, the researchers believe that the cause of the disease lupus connection with poor environmental conditions. But unfortunately, they still could not determine which factor is the most powerful cause of a person suffering from lupus.



2. Hormone

In fact, women are 9 times more at risk of developing lupus than men. This phenomenon can be explained by the sex hormone that is produced the immune system of women and men, where both are clearly different. A woman's body produces and uses the hormone estrogen more, while the male body is dependent on hormones called androgens.

Estrogen is known as hormone “immuno-enhancing“, which means that women have a stronger immune system than men, given the need evolutionary for a woman to survive, plays a role in childbirth, and the nurture of their children. However, as a result, when the immune system is turning around to attack the body, women will be more prone to autoimmune diseases.

3. Environment

In addition, several environmental factors have been attributed to be the cause of the disease lupus. Researchers have link between lupus and a variety of environmental toxins, for example smoking rooms, gel sodium, silica, and mercury. The Virus herpes zoster (the virus that causes shingles), and cytomegalovirus is predicted to also be one of the causes of a person affected by lupus.

Symptoms of lupus has a different character in each person, this makes lupus more difficult to detect. To date there is no specific test to detect the disease lupus. Even so, the doctor will usually advise the patient to do some tests, like urine tests, blood tests, and antibody tests.

To diagnose whether a person having the disease lupus, the doctor will also typically look at family health history, perform health checks in general, as well as recommend that the patient undergo a biopsy of the skin and kidneys.

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